Contraline Inc.  logo
Biotech/Pharma

Contraline Inc.

Contraline is a Charlottesville-based company working at the forefront of reproductive medicine.

CORE INFO

$92.5M
Total Funding
Series B
Round
2015
Founded
27
Team Size
Charlottesville, Virginia, USA
Headquarters

Contraline Inc. is a biotechnology company focused on developing innovative male contraceptive solutions, including a topical gel and a non-hormonal implant, aimed at providing safe and reversible options for men and couples.

  • Contraline recently secured $92.5 million in Series B funding, co-led by BVF Partners L.P. and RA Capital Management, to advance its NES/T Gel into late-stage development.biospace.com
  • BioSpace reported on Contraline's Series B funding, highlighting its significance in advancing the NES/T Gel, a male contraceptive, into late-stage development.biospace.com

WHY WE WOULD WORK AT CONTRALINE INC.

Innovative Mission

Join a team dedicated to expanding reproductive choices for men and couples worldwide through groundbreaking male contraceptive solutions like NES/T Gel and ADAM.

Cutting-Edge Technology

Work with advanced biotechnology in developing novel male contraceptives that prioritize safety, effectiveness, and reversibility, setting new standards in reproductive health.

Growth Opportunities

Be part of a rapidly growing company that has expanded from 7 to 27 employees, with significant funding to propel your career forward in a dynamic environment.

Competitive Compensation

Benefit from a robust funding history, including $92.5 million in Series B financing, ensuring competitive salaries and resources for employee development.

Impactful Work

Contribute to meaningful clinical advancements, such as the successful Phase 2b trial of NES/T Gel, making a real difference in the lives of couples seeking contraceptive options.

Collaborative Culture

Join a passionate team of experts in biotechnology, fostering a collaborative environment that values innovation and encourages diverse perspectives in problem-solving.

MARKET AND TRACTION

TOTAL ADDRESSABLE MARKET

  • The global male contraceptive market is an emerging sector with significant growth potential as awareness and demand for male contraceptive options increase.

  • Contraline aims to capture a share of this market by providing innovative solutions that address unmet needs in male reproductive health.
  • KEY METRICS

    ✦ KEY METRIC
  • Total funding raised to date is approximately $113.98 million across multiple funding rounds.

  • The latest funding round, Series B, raised $92.5 million in June 2026 to advance the NES/T Gel into late-stage development following a successful Phase 2b clinical trial.
  • GROWTH TACTICS

  • Contraline is focusing on advancing its NES/T Gel and ADAM implant through clinical trials to ensure efficacy and safety before market introduction.

  • The company is expanding its team, growing from 7 employees at founding in 2015 to 27 employees as of recent reports, to support its development efforts.
  • COMPETITIVE ADVANTAGE

  • Contraline's NES/T Gel is designed to suppress sperm production while maintaining normal testosterone levels, offering a unique hormonal approach to male contraception.

  • The ADAM implant provides a non-hormonal option that blocks sperm in the vas deferens without affecting sensation or ejaculation, catering to diverse preferences among men.
  • MARKET POSITION

  • As a clinical-stage biotechnology company, Contraline is positioned at the forefront of male contraceptive innovation, with two promising products in development.

  • The successful completion of a Phase 2b clinical trial for NES/T Gel demonstrates the company's commitment to advancing male reproductive health solutions.
  • PRODUCT AND TECH

    NES/T Gel

    NES/T Gel is a once-daily topical gel that combines a synthetic progestin with testosterone to effectively suppress sperm production while maintaining normal testosterone levels. This innovative male contraceptive solution aims to provide a safe, effective, and reversible option for men.

    ADAM Implant

    The ADAM implant is a long-lasting, non-hormonal contraceptive device designed to block sperm in the vas deferens without affecting sensation or ejaculation. This technology represents a significant advancement in male contraception, offering a reversible solution that enhances reproductive choices for men.

    Clinical Development

    Contraline is focused on advancing its products through rigorous clinical testing, including the successful completion of a Phase 2b trial for NES/T Gel. This commitment to clinical development ensures that their contraceptive solutions are both effective and acceptable to users.

    Biotechnology Innovations

    As a clinical-stage biotechnology company, Contraline leverages cutting-edge research and technology to develop novel male contraceptive solutions. Their focus on innovation in reproductive health aims to expand the options available for family planning.

    Funding for Advancement

    Contraline has raised approximately $113.98 million in funding, including a recent $92.5 million Series B round, to support the late-stage development of NES/T Gel and other products. This financial backing is crucial for bringing their innovative contraceptive solutions to market.

    COMPANY CULTURE

    Values

  • Innovation in reproductive health

  • Commitment to safety and efficacy

  • Focus on providing reversible contraceptive options

  • Empowering men with reproductive choices

  • Collaboration and teamwork in research and development
  • Operating Principles

  • Prioritize user acceptability in product development

  • Emphasize ethical practices in clinical trials

  • Foster an inclusive environment for diverse perspectives

  • Maintain transparency with stakeholders and investors
  • Benefits

  • Opportunity to work on groundbreaking male contraceptive solutions

  • Support for professional development and growth

  • Collaborative and dynamic team environment

  • Competitive compensation and benefits package
  • Learning & Growth

  • Continuous learning opportunities in biotechnology

  • Encouragement of innovative thinking and problem-solving

  • Access to mentorship from experienced leaders in the field

  • Participation in industry conferences and workshops
  • Team Cadence

  • Regular team meetings to align on goals

  • Open communication channels for feedback and ideas

  • Agile project management to adapt to changing needs

  • Celebrating milestones and achievements together
  • HIRING SIGNAL

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    KEY COMPANY ANNOUNCEMENTS

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    5 announcements · ranked by importance
    Jun 10, 2026FUNDINGForm D filing — Contraline, Inc. (CIK 0001818752)sec.gov
    Jun 2, 2026FUNDINGContraline raises $92.5M for male contraceptive gelaxios.com
    Jun 2, 2026FUNDINGContraline Announces $92.5 Million Series B Financing to Advance NES/T Male Contraceptive into Late-Stage Developmentbusinesswire.com
    Apr 5, 2022FUNDINGForm D filing — Contraline, Inc. (CIK 0001818752)sec.gov
    Oct 21, 2021FUNDINGContraline Raises $10M in Series A Funding - FinSMEsfinsmes.com